Ecofeminism as the Movement Towards a New Humanity

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POWER– the capacity or ability to direct or influence the behavior of others or the course of events.

Currently, there are close to 7.8 billion people populating our world. Out of those 7.8 billion individuals only 1% of the population owns more than half of the worlds wealth (Frank). Unfortunately, privilege seems to roll off the back of this 1% leaving the stench of power in its wake. And as unjust and absurd as our reality may seem, “liberation theologist” Ivone Gebara argues that the rest of the  of population have become complacent to the patriarchal global capitalist system. Gebara goes on to explain that due to this cultural and economic globalization we have become, “people living without a social dream, without thinking and acting in a historical direction… we do not know who we are. we live as we live without the radical or tedious questions coming from feminist philosophers” thus we are invited “to forget these…questions that do not fit in a world of globalization” (Gebara 100). Sadly, this unequal distribution of economical power has lead to a growing number of marginalized people, in particular marginalized women.  As we’ve learned through previous blog post a “females poverty depends on the destruction of ecosystems” (Gebara 96).

However, there are plenty of women world wide who are willing to fight for the creation of a new world/ utopia in which women and men can establish a harmonious relationship based on justice, equality, and solidarity in order to create a healthier earth. Feminist lead activism such as the 1973  Chipko movement organized to resist the destruction of the India forest, has inspired many. In particular, The Chipko movement showed as rural villagers (mostly women) linked hands “hugging” the trees to impede the loggers in a peaceful protest. More recently in the United States, Native American women in Dakota are leading the movement against the access pipeline which threaten to run through their sacred land and culture. As the backbone of every tribe and indigenous community the Native women in Dakota are bound to protect their people’s basic human right to clean water, while fighting against a history of misogyny, racism, and abuse by law enforcement (Levin).

Yet, Norther Native American women aren’t the only ones forced to protect their lands. Plenty of indigenous women are suffering at the hands of powerful companies, due to a long history of voilence. In countries like Guatemala the link between the destruction of the environment and the destruction go indigenous population can be directly traced to the 16th century Spanish conquest of indigenous land, people, and resources. Due to the unequal distribution of land in Guatemala only a small number of elites own the vast majority of arable land leaving most of the indigenous population living in steep and rocky mountain slopes that are both dangerous to work and difficult to cultivate enough crops to feed one family let alone a whole community (Hallum-Montes 7). Within these highland communities women contribute between 21 and 30% of the total labor time needed to grow expert crops in addition to various task like meal preparation, collection of firewood, and water. As a result, Guatemala Indigenous women are leading the way in environmental awareness publicly addressing the soils loss of fertility, the increasingly unpredictable seasons, and the erratic rainfall.

It is important to keep in mind as active Ecofeminist to stay present. While rejecting the feeling of complacency and the idea that we can only save some instead of working to changing the whole system. We can no longer stand around an accept the problems that lay before us. Instead we must take action and reclaim our own power and intern return natures. 

Sources:

https://www.cnbc.com/2017/11/14/richest-1-percent-now-own-half-the-worlds-wealth.html

http://edugreen.teri.res.in/explore/forestry/chipko.htm

Hallum-Montes, R. (2012). “PARA EL BIEN COMÚN” INDIGENOUS WOMEN’S ENVIRONMENTAL ACTIVISM AND COMMUNITY CARE WORK IN GUATEMALA. Race, Gender & Class, 19(1/2), 104-130.

Gebara, I. (2003). Ecofeminism: A Latin American perspective. Cross Currents, 53(1), 93-103,142.

https://www.theguardian.com/us-news/2016/nov/04/dakota-access-pipeline-protest-standing-rock-women-police-abuse

54 thoughts on “Ecofeminism as the Movement Towards a New Humanity”

  2. Nonetheless, we’ve shown that the interior peptide bonds of the glycoalkylated tripeptides, 12a and
    12b, are steady over several days to pronase.
    These results had been stunning and disappointing as a outcome of Ac-KPV-NH2 (12c)
    has been reported as an anti-microbial agent [12,19,37].

    Singh and Mukhopadhyay independently described the 90%
    staphylocidal activity of Ac-KPV-NH2 (12c) at micromolar
    concentrations and 50% activity within the nanomolar focus
    range [37]. Charnley et al. reported broad range activity in opposition to each Gram-positive and Gram-negative bacteria [19].
    Their examine included five tripeptides, Ac-KPV-NH2 (12c) amongst them; not considered one of the tripeptides were lively against
    the panel of pores and skin pathogens, indicating MICs larger
    than 100 μM. By analyzing the interplay between KPV Peptide and immune operate, researchers can elucidate the mechanisms by which this remedy modulates immune responses,
    thereby paving the best way for optimized treatment strategies.

    The period to look at outcomes from KPV Peptide therapy may vary
    based mostly on the situation being treated and the particular therapeutic advantages focused.

    After transient transfection of IEC Caco2-BBE with an NF-κB-dependent luciferase reporter plasmid, IL-1β remedy led to a ~6-fold increase in luciferase exercise in comparison with
    untreated cells (Figure 1A). However, co-incubation of Caco2-BBE cells with KPV (10 nM) and
    IL-1β considerably decreased the IL-1β-induced luciferase exercise (Figure 1A).
    To verify that KPV decreases NF-κB activation, IκB-α degradation and phosphorylation which can account for NF-κB activation, had been assessed by immunoblot analyses in Caco2-BBE cells treated with IL-1β ± KPV.
    We discovered high ranges of IκB-α degradation 20 minutes after IL-1β stimulation whereas,
    within the presence of KPV, IκB-α degradation was reduced presently (Figure 1B).
    IκB-α stage then returned to the baseline degree after 180 minutes of IL-1β stimulation whereas, within the
    presence of KPV, IκB-α baseline ranges were reached within 90 minutes
    of stimulation (Figure 1B). Moreover, IκB-α was nonetheless phosphorylated
    after 45 minutes of IL1-β stimulation however not within the
    presence of KPV (Figure 1C). Collectively, our outcomes present that KPV
    delays NF-κB activation and in addition shortened the delay of IκB-α restoration, suggesting that KPV decreases the duration of NF-κB activation.
    Reported points are delicate, corresponding to transient pores and
    skin irritation or GI upset at greater experimental doses.
    KPV is a brief tripeptide (Lysine–Proline–Valine) derived
    from α-MSH, a hormone concerned in immune regulation. It retains the strong anti-inflammatory
    exercise of α-MSH without its broader hormonal effects.
    As A Outcome Of KPV is still a research-only peptide,
    there aren’t any standardized scientific dosing pointers.
    What exists comes from preclinical research and experimental protocols utilizing oral, injectable,
    or topical delivery.
    KPV peptide has potent anti-inflammatory effects that assist treat inflammatory bowel illness and autoimmune issues.
    KPV’s most extensively researched utility is within the therapy of inflammatory bowel conditions,
    the place its distinctive supply mechanism and targeted effects create remarkable enhancements.

    This precision-targeted approach explains why KPV can ship such highly effective anti-inflammatory effects with minimal impact on healthy tissues
    or normal immune perform. One Other research found that KPV accelerates corneal
    wound therapeutic, with handled corneas absolutely
    healing inside 60 hours, in comparability with slower
    healing within the placebo group. The healing appears linked to nitric oxide (NO) activity, as its
    results were blocked by a nitric oxide synthase inhibitor (l-NAME).
    In vitro results additionally confirmed KPV enhances cell viability, suggesting
    a broader reparative role tied to NO dynamics [6].
    We beforehand showed that human monocytes categorical a practical hPepT1 protein (18).
    PepT1 expression in immune cells supplies the opportunity to ship small peptides into cells that are actively concerned in intestinal irritation. Due To This Fact, immune cells might take part in the discount of colitis
    by way of KPV-mediated inhibition of immune responses.

    We show that the anti-inflammatory effect of KPV is not melanocortin receptor-mediated but
    PepT1-mediated. Moreover, it was just lately demonstrated that KPV doesn’t bind to MC1,three,5R (32) and doesn’t compete with α-MSH (20), indicating a
    non-MCR mechanism. Apparently, we found, in Caco2-BBE cells, that hPepT1
    has a high affinity for KPV (Km ~160 μM) that enables low doses of KPV to be efficiently
    focused to the intracellular compartment.

    For example Gly-Sar, which is essentially the most
    generally used PepT1 substrate, has a Km ≥ 1 mM
    in Caco2-BBE cells (33). Indeed the Km is ~700 μM and just one research reported kinetic experiments in immune cells exhibiting that the Km of
    hPepT1 for its substrates Gly-Sar and fMLP have been ~2 mM (18).

    The KPV peptide mechanism of motion entails the direct inhibition of inflammatory pathways within cells, notably by reducing the production of pro-inflammatory cytokines and inhibiting key transcription elements involved in inflammation. Thus, KPV mediates its major anti-inflammatory impact via the nuclear
    transport system and independently of melanocortin receptors.
    The pharmaceutical development of KPV as an anti-inflammatory therapy may
    subsequently depend upon the diploma to which it could be
    focused to specific interactions between importin molecules and their protein cargo.
    This transcription issue is a central regulator of immune responses and inflammation. By blocking NF-κB’s translocation to the
    nucleus, KPV peptide successfully reduces the synthesis and launch of pro-inflammatory cytokines,
    such as TNF-alpha and interleukins.
    Its unique combination of anti inflammatory effects, antimicrobial properties,
    and versatile delivery strategies positions KPV as
    a leading choice in the evolving landscape of peptide remedy.
    One research demonstrated that KPV peptide considerably reduced irritation in DSS-induced colitis
    fashions, a typical method used to review inflammatory bowel disease (IBD) in laboratory
    settings. By inhibiting proinflammatory cytokines, KPV helped
    decrease total intestinal inflammation, making it a promising therapy for conditions like
    Crohn’s disease and ulcerative colitis. This operate is
    particularly beneficial for individuals coping with circumstances
    like Crohn’s disease, ulcerative colitis, and other types of
    inflammatory bowel illness (IBD). In truth, studies have shown that KPV significantly decreased inflammation in intestinal epithelial cells,
    which is a crucial consider maintaining gut well being.

    The growing interest in peptide remedy analysis has highlighted KPV as an active bioregulator fragment worth investigating.
    Unlike conventional anti inflammatory compounds, analysis exhibits this tripeptide might have
    unique immune modulation capabilities while being selective in its
    inflammatory responses.

    References:

    gt.clarifylife.net

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